Sign up for the riboPOOL Webinar by siTOOLs Biotech.

Webinar: riboPOOL for Efficient and Flexible Ribosomal RNA Depletion

Current solutions to remove ribosomal RNA (rRNA) prior to   Next-Generation RNA Sequencing (RNA-Seq) are costly and limited to   well-studied species. riboPOOL by siTOOLs Biotech is an efficient and   flexible solution found to outperform current kits and can be applied  to  any species or abundant RNA.

Learn about siTOOLs Biotech’s   high complexity oligo pooling technology and understand how the diverse   range of riboPOOLs can be applied for single or multi-species samples,   metatranscriptomics and other demanding sample types.
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About siTOOLs Biotech

siTOOLs Biotech from Munich makes advanced genetic tools for better results in preclinical research. siTOOLs’ core technology uses high complexity pooling of optimally designed oligos to increase targeting specificity and efficiency in multiple applications. Their products include complex siRNA pools (siPOOLTM) for reliable RNA interference-based gene silencing and complex pools of biotinylated probes for any-species ribosomal RNA depletion prior to RNA-Seq (riboPOOLTM) or targeted enrichment of RNA-protein complexes for biochemical analysis (raPOOLTM).
siTOOLs also offers experimental and bioinformatic services that includes access to Phenovault, a carefully curated RNAi screening database and analysis suite to aid novel target identification. With expertise in reagent development and research services, siTOOLs is a valuable partner for accelerating scientific discoveries and drug development.

How do riboPOOLs differ from existing ribosomal RNA (rRNA) depletion solutions?


The riboPOOLs are a defined complex pool of biotinylated DNA probes  designed with proprietary algorithms. Compared to other solutions,  riboPOOLs are non-polyA-dependant, enzyme-free, highly efficient and can  be used to deplete rRNA or other abundant RNA from single or multiple  species.

Anna Liznar

siTOOLs Biotech

Speaker of the Webinar

Can riboPOOLs be used on ribosome profiling samples?


Yes. We have developed a robust riboPOOL for human/mouse/rat ribosome profiling samples. The h/m/r ribosome profiling riboPOOL targets gaplessly the ribosomal RNA. Moreover, abundant rRNA contaminations are evenly depleted due to optimal riboPOOL design. 


*** human/mouse/rat ribosome profiling riboPOOL available from Nov 1st 2020 ***



Thank you for your interest.

Questions? Write us an email on info@sitools.de